Poster 1130, Language: EnglishAgarwal, Deepali S. / Kumar, Adarsh / Manjunath, B. C.
Background: Early childhood caries (ECC) is a public health problem. Studies have reported propinquity between ECC and maternal knowledge, attitudes, practices, age, education, and smoking habits.
Objective: To assess the evidences of association between maternal factors and early childhood caries.
Method: This comprehensive literature search was conducted for the period 2006 to 2016. Databases included Pubmed, Google Scholar, and cross references. Two authors independently selected the studies and extracted the data. Mesh terms "caregivers", "mother", "caries", and "knowledge" were used. 506 articles were selected after removing the duplicates and those that did not match the search criteria. Methodological quality assessment was done using a tool based on Strobe and NIH checklists for observational studies.
Results: 10 papers were finally included. The mothers' caries status, knowledge, socioeconomic status and smoking habits significantly affect the caries status of children, whereas the effects of education status and breast feeding were inconclusive. The studies were heterogenous. There was a lack of studies on children aged < 30 months.
Conclusion: This systematic review of observational studies indicates Level IV evidence for an association between maternal factors and early childhood caries.
Dental public health significance: Oral health promotion of mothers can significantly reduce ECC.
Keywords: caregivers, mother, caries, knowledge
Poster 1131, Language: German, EnglishLiebehenschel, Niels
Head and neck tumours are among the top ten of all tumour entities. They make up a total of 30%, with 90% of these being squamous cell carcinomas. Upper jaw carcinoma is one of the rare sites in the mouth and is below 35%. The occurrence in childhood is extremely rare. Only a few publications are available. With 1800 childhood malignancies per year, the probability of occurrence is less than 0.2%. Boys are 20% more affected than girls. The prognosis quoad vitam of childhood-treated cancer cases under the age of 15 years at initial diagnosis is 81% over the next 15 years. The exclusion of typical childhood risk factors such as EBV-associated carcinoma or genetic disposition suggests a sporadic occurrence.
We present a 13-year-old patient with an exophytic upper jaw carcinoma. Initially, neoplasia was histologically noted as a pseudoepithelial hyperplasia (PEH). After referring the sample to the Center for Dermatopathology and the Children's Cancer Registry, the diagnosis of carcinoma was revealed. Staging was performed, EBV and HPV were excluded as well as tumour predisposition syndrome. Complete tumour resection was performed, followed by reconstruction with Bichat's fat graft, palatal rotation-flap, and a Rehrmann-flap. No further therapy was performed. The young patient currently remains free of cancer after 3 years and is regularly seen at paediatric hematology and oncology departments and the oral and maxillofacial surgery. Quarterly clinical and MRI controls are performed. Bony reconstruction with free autologous iliace crest graft was performed at age 16, followed by implantation.
Keywords: Oral cancer, child
Poster 1132, Language: EnglishMahmoodi, Benjamin / Weusmann, Jens / Braun, Ben / Azaripour, Adriano / Willershausen, Brita
Aim: The incidence of traumatic dental injuries (TDIs) is higher in evenings and on weekends. They require early and appropriate management to minimise complications and to save the affected tooth. Consequently, many patients present in dental emergency services, which operate outside regular consulting hours. The aim of this study was to analyse the TDI cases in a dental emergency service unit of a university hospital over 4 years. Methodology: All patients with TDIs between 2010 and 2013 were determined from the hospital database and subjected to further analysis. Demographic data, classification of trauma (according to the WHO), teeth involved, and cause of trauma were evaluated.
Results: Of 16 301 patients who received treatment in the dental emergency service over a period of 4 years, 1305 (8.0%) came due to TDIs. Average age was 14.4 years (range: 0.6- 88.1). More than half of the trauma patients (54.2%) were under the age of ten and about two-thirds (74.5%) under twenty. Males experienced trauma more often than females (range 1.5 : 1). Nearly half of cases (48.2%) occurred on weekends. The most common diagnosis was subluxation (27.8%), followed by uncomplicated enamel-dentin fracture (25.9%), and lateral luxation (21.7%). 355 patients (27.2%) had an additional soft tissue injury. In 48.6% of cases only one tooth was involved, in 33.5% two. The permanent dentition was injured in 56.6% of cases, the primary dentition in 41.1%. The maxillary central incisors were affected in 79.2% of cases. The most common causes of TDIs were falls (54.6%) and sport accidents (13.4%).
Conclusions: The prevalence of TDIs in the dental emergency unit was high. Due to the complexity of management, possible complications, and lifelong consequences, the dentist on duty as well as the one providing further treatment have to be aware of the endodontic and surgical measures. A regular update of the dentists' knowledge about traumatology is required and more attention should be given to the prevention of trauma.
Keywords: TDI, dental trauma, traumatic dental injuries, emergency
Poster 1133, Language: EnglishPetkova, Silviya / Bolyarova, Theodora
Introduction: Furcation lesions are a common symptom of moderate or severe periodontitis. Making an accurate diagnosis and conducting the proper treatment is a challenge in dentistry.
Aim: Analyse the competence of the Bulgarian dentists concerning the diagnosis and treatment of furcation lesions. Material and methods An anonymous survey among 150 dentists about the knowledge and the use of furcation lesion diagnostic methods and therapeutic approaches was conducted.
Results: For Class I furcation lesions, only 32.9 % of the dentists would employ odontoplasty. For Class II furcation lesions - only 9.4 % would use regenerative therapy. For Class III furcation lesions - only 1/3 of the respondents would perform resective periodontal surgery, odontoplasty, or extraction.
Conclusion: Additional training to establish the exact diagnostic and treatment of furcation lesions is necessary. This will result in better treatment of the periodontitis.
Keywords: furction lesions, odontoplasty, regenerative therapy, diagnosis/furcation lesions
Poster 1134, Language: German, EnglishRott, Thea / Imhof, Thomas / Sotiriadou, Isaia / Shinde, Vaibhav / Höfer, Karolin / Menzel, Carolin / Derman, Sonja / Sachinidis, Agapios / Koch, Manuel / Noack, Michael J.
Aim: The aim of this study is to investigate the impact of various amelogenin preparations on the attachment and proliferation of periodontal ligament cells (PDL-cells) on periodontally infected root surfaces.
Material & Methods: Root surfaces of periodontally infected, extracted human teeth were treated with scaling and root planing (SRP) and subsequently coated with three different amelogenin preparations, the clinically well-established Emdogain, a recombinant human wildtype-amelogenin (rH174), and a modified recombinant human wildtype-amelogenin (RGD-amelogenin). For modification, the tripeptide Arg-Gly-Asp (RGD) loop from fibronectin was inserted into the rH174 nucleotide sequence at the C-terminal ending using polymerase chain reaction (Imhof et al., 2015). PDL-cell attachment was measured after 30 minutes. PDL-cell proliferation on coated periodontally infected root surfaces which were treated with SRP was analysed after 72 h and compared with healthy root surfaces (positive control), periodontally infected, untreated root surfaces (negative control) or root surfaces that were exclusively treated with SRP. Cell morphology and distribution was documented using a scanning electron microscope.
Results: The attachment analysis revealed a significant increase in PDL-cell attachment after coating with Emdogain compared to coating with wildtype-amelogenin (p
Keywords: PDL-cell, attachment, proliferation, periodontal regeneration, Emdogain, amelogenin, fibronectin, RGD
Poster 1135, Language: EnglishPhogat, Ritu / BC, Manjunath / Kumar, Adarsh / Bhukal, Anuradha
Introduction: Dental caries are a major public health problem. Various attempts have been made to deal with the problem. One of them is reducing sugar consumption, but it is not so effective. Tobacco-use control programs, however, have shown that substitution therapy-replacing a harmful habit with a positive, more culturally acceptable practice-can be effective. Xylitol has attracted much attention as an alternative sweetener. The effect of xylitol on caries development relates to its non-cariogenicity and to the beneficial effect of substituting sucrose with xylitol in chewing gums.
Objective: Investigate the effectiveness of xylitol chewing gum in the prevention of dental caries. Methods: A systematic literature survey was carried in electronic data bases like Pubmed, Google Scholar, and the Cochrane Library with MeSH terms "xylitol chewing gum", "dental caries" in the English language. The authors extracted data on study characteristics, dental caries increment, and the main findings.
Results: 199 potentially relevant studies were identified. The 10 articles selected for this review showed that the use of xylitol chewing gum is associated with prevented fractions ranging from 33.33 percent to 63.03 percent.
Conclusions: The evidence suggests that xylitol chewing gum has a caries-reducing effect. Further well-designed randomised trials are needed to confirm these findings.
Keywords: xylitol, chewing gums, dental caries
Poster 1136, Language: German, EnglishSchnabl, Christina Lucia / Günther, Lutz / Rustemeyer, Jan
Ein FallberichtEinleitung: Der "solitäre mediane Schneidezahn des Oberkiefers" (solitary median maxillary central incisor, SMMCI) ist eine seltene Anomalie, welche allerdings häufig mit Fehlbildungen wie z.B. einer Stenose der Apertura piriformis auftritt [1-3]. Der SMMCI selbst stellt keine Gesundheitsbeeinträchtigung dar und bedarf daher im Allgemeinen keiner Therapie. [1]. Hingegen ist die Stenose der Apertura piriformis bei Neugeborenen eine potenziell lebensbedrohliche Erkrankung [2, 4].
Falldarstellung: Nach der Geburt eines männlichen Säuglings zeigte dieser eine schwere obstruktive Dyspnoe und musste daraufhin orotracheal intubiert werden. Weiterhin wurden mehrere Anomalien, einschließlich urogenitaler und kraniofazialer Fehlbildungen festgestellt. Die Diagnostik mittels Computertomographie zeigte eine Stenose der Apertura piriformis mit einem Restlumen von nur 4,9mm und einem SMMCI. Nach zunächst konservativer Therapie mit Einführung einer 3,0mm Tube in die linke Nasenhöhle war eine ausreichende und spontane Nasenatmung möglich. Die Entfernung des Röhrchens folgte nach sieben Tagen und der Säugling konnte unter Anwendung von abschwellenden Tropfen nach Hause entlassen werden. Nach sieben Monaten wurde der Säugling erneut wegen akuter Atemnot stationär aufgenommen. Daraufhin erfolgte über einen vestibulären Zugang eine Erweiterung der Naseneingänge durch Abtragung der Stenose. Postoperativ wurden 3,0mm Tuben in beide Nasengänge für zehn Tage eingebracht. Über einen Kontrollzeitraum von 6 Monate zeigte der Säugling eine freie Nasenatmung und unauffällige Schleimhautverhältnisse.
Schlussfolgerung: Die Behandlung einer Stenose der Apertura piriformis ist von der Schwere der Symptomatik, den Begleiterkrankungen und der allgemeinen Prognose des Kindes abhängig. Bei gering ausgeprägter Behinderung der Atmung ist eine abwartende Haltung gerechtfertigt. Da Säuglinge obligate Nasenatmer sind, birgt allerdings eine anhaltende Nasenatmungsbehinderung eine potenzielle Lebensgefahr, so dass frühzeitig eine chirurgische Abtragung der Stenose erforderlich wird.
Keywords: Stenose der Apertura piriformis, solitärer einzelner mittlerer oberer Schneidezahn, Fehlbildungen, assoziierte Anomalien
Poster 1137, Language: EnglishM., V. Harshitha / Eshwar, Shruthi / Srivastava, B. K. / Jain, Vipin / Rao, Rekha / Swamy, Madhu Nirajan
Introduction: Despite the growing strength of social networks, television advertising is still the most influential medium in people's purchasing decisions, particularly children.
Aim: To assess the influence of television advertisements on the purchasing behaviour of foods detrimental to oral health and their impact on caries prevalence among school children and to analyse the extent and nature of food advertising in a sample of kids' television programmes focusing on the foods detrimental to oral health.
Methodology: A non-randomised, uncontrolled questionnaire-based study was conducted among 480 children aged 6-14 years attending the schools of Bangalore city, followed by an oral examination. Based on the response, kids' channels were analysed for the nature and extent of food advertisements that are detrimental to oral health. Oral health education was given to all the children about the ill-effects of foods that were advertised on television. A post intervention questionnaire was administered after one month to evaluate the effect of intervention.
Results: Among 480 children, 14.1% reported that they purchase food products once in a month, 57.2 % once in a week, 26% every day and only 0.02% have never purchased any, and there was a significant association (p
Keywords: Television advertisements, caries prevalence, purchasing behavior, children, health education
Poster 1138, Language: EnglishGore, Rucha Diwakar
Background: Oral squamous cell carcinoma is the sixth most common cancer worldwide and is one of the leading causes of death, especially in developing countries like India. Cancer is a hyperproliferative disorder that is usually managed with the help of chemotherapeutic agents that are toxic not only to tumour cells, but also to normal cell in many ways. In addition, these agents are very expensive and thus not affordable for most. Moreover, these agents cannot be used for the prevention of cancer. In contrast, the traditional herbal medicines used from ancient days in India are generally known to be free of the deleterious effects and are inexpensive but effective. Wheatgrass is the young grass of the wheat plant "Tritcum aestivum Linn." from the family Poeaecae (Graminae). It contains a plethora of vitamins, mineral, amino acids, and vital enzymes like dismutase superoxide and cytochrome oxydase. These enzymes play an important role in the anticancer approach of this herbal product. It is also called "green blood' because of its high chlorophyll content, which accounts for 70% of its chemical composition. Chlorophyll bears a structural similarity with hemoglobin and thus results in a high oxygen supply to all the body tissues.
Aim of the study: To analyse the effect of wheat grass extract on an oral squamous cell carcinoma (OSCC) cell line.
Materials and methods: KB (Mouth Epidermal Carcinoma Cells) was used for the present study. Aqueous extract of wheat grass was prepared in the institution. The effect of aqueous extract was studied on an OSCC cell line (KB cell line).
Conclusion: Inhibition of cancer cell proliferation by aqueous extract of wheatgrass, which is abundantly grown in India.
Keywords: Wheatgrass (Triticum aestivum), Oral squamous cell carcinoma cell line, Oral squamous cell carcinoma
Poster 1139, Language: German, EnglishBenz, Korbinian / Kozmacs, Carla / Jackowski, Jochen
Einleitung: Als maligner Weichteiltumor entwickelt sich das Rhabdomyosarkom (RMS) aus den Zellen der quergestreiften Muskulatur. Bei den unter 15-Jährigen wird die Jahresinzidenz auf 1:224.000 geschätzt. Der Median des Diagnosealters liegt bei 5 Jahren. Das Rhabdomyosarkom kann überall im Körper entstehen, auch an Stellen, in denen keine quergestreifte Muskulatur vorhanden ist. Kopf- und Halsbereich sind zu 40% betroffen, davon die Orbitae und die paranasalen Sinus am häufigsten. Ursache und Entstehung sind bis heute weitgehend unbekannt. Die Reihenfolge und die Durchführung der einzelnen Therapiearten hängt von den Tumor- und Patientenbedingten Risikofaktoren ab.
Fallbericht: Bei einer heute 17-jährigen Patientin wurde im Alter von 3 Jahren ein Rhabdomyosarkom in der rechten Fossa pterygopalatina mit intrakranieller Ausbreitungstendenz diagnostiziert und durch Exzision mit anschließender Radiatio und Polychemotherapie erfolgreich behandelt. In Folge kam es zu einer vollständigen Anästhesie im Versorgungsgebiet des N. trigeminus rechts und einem Visusverlust des rechten Auges. Das Schädelwachstum entwickelte sich auf der bestrahlten Seite geringer als auf der nicht betroffenen Seite, Maxilla und Mandibula sind mikrognath. Unter dem Aspekt der Lagebeziehung beider Kiefer ließ sich eine Angle-Klasse III feststellen. Die Patientin klagte auch über die bereits seit Jahren bestehende intraorale Situation, da sämtliche Zähne einen Lockerungsgrad II-III aufwiesen mit der Folge einer erschwerten Ingestion. Zusätzlich traten Schmerzen im Bereich der Kiefergelenke und der Kaumuskulatur auf. Röntgenologisch zeigten sich in der Panoramaschichtaufnahme multiple Nichtanlagen der Dentes permanentes und rudimentär entwickelte Apices. Die Capites mandibulae und Processi coronoidei erschienen degeneriert und abgeflacht. Die Patientin wünscht neben der Herstellung einer akzeptalen Funktionalität auch eine Verbesserung des ästhetischen Erscheinungsbildes.
Methode: Nach kieferorthopädischem und Mund-Kiefer-Gesichtschirurgischem Konsil wurde eine Umstellungsosteotomie in Kombination mit Implantat-vermittelten Rehabilitation aufgrund der nicht vorhersagbaren Heilungstendenz als nicht indiziert angesehen. Daraufhin wurde bei der Patientin eine Bisshebung über herausnehmbare Aufbissschienen eingeleitet, um auf diese Weise vielleicht eine Interkuspidation zu erreichen und die Belastbarkeit der Kiefergelenke, der Muskulatur und der Zähne zu evaluieren. Nach 6-monatiger problemloser Tragezeit wurde im Ober- und Unterkiefer ein herausnehmbarer Interims-Zahnersatz auf Basis einer Tiefziehschiene eingegliedert. Die noch vorhandenen Zähne dienten der Führung bei der Inkorporation und zur Erzielung einer leichten Friktion. Nach 3-monatiger Tragezeit in Kombination mit logopädischer Unterstützung berichtete die Patientin von einer wesentlichen Verbesserung vor allem im sozialen Umfeld aufgrund der verbesserten Ästhetik. Allerdings ist in den nächsten Monaten noch eine schrittweise Korrektur im Bereich der Ingestion und des Sprachbildes avisiert. Als definitive Versorgungsvariante wird unsererseits eine Versorgung mittels Galvanoteleskopen angestrebt.
Zusammenfassung: Da Rhabdomyosarkome in sensiblen Körperregionen (u. a. Kopf-Hals-Bereich) lokalisiert sind, ist die Behandlung anspruchsvoll und multidisziplinär. Das Therapieziel ist die Befund-zentrierte orale Rehabilitation der jungen Patientin im Sinne einer personalisierten Medizin.
Keywords: Embryonales Rhabdomyosarkom, orale Rehabilitation