Online OnlyDOI: 10.11607/prd.2474, PubMed ID (PMID): 28817143Pages 290-296, Language: EnglishIorio-Siciliano, Vincenzo / Blasi, Andrea / Nicolò, Michele / Iorio-Siciliano, Alessandro / Riccitiello, Francesco / Ramaglia, LucaThe aim of this study was to evaluate the clinical remodeling of the alveolar socket following the application of bovine-derived xenograft collagen and collagen membrane compared to natural spontaneous healing during the first 6 months following tooth extraction. A total of 20 patients with 20 fresh alveolar sockets were randomly allocated into a test or control group. After a 6-month follow-up period, surgical reentry was performed and implants were placed. Significant statistical differences were recorded in terms of vertical and horizontal bone changes between the test and control groups. Within the limitations of this study, socket preservation procedures may provide more favorable conditions for subsequent implant placement.