PubMed ID (PMID): 29379903Pages 50-64, Language: EnglishDel Curto, Filippo / Saratti, Carlo Massimo / Krejci, IvoSince the first introduction of the Cerec system (Sirona) in the early 1980s, the use of computer-aided design/computer-aided manufacture (CAD/CAM) technology has spread widely in modern adhesive dentistry. Thanks to this innovative technology, it has been possible to carry out chairside restorations fully managed by the clinician, with the advantages of lower costs for the patient, more rapid execution of the restorations, and the exclusion of the provisional phase. With further improvements in chairside technologies and materials, specifically in the field of composite resin blocks, it is now possible to fabricate multiple ultrathin, minimally invasive or even noninvasive restorations in one single appointment. The clinical case presented here was solved using an innovative approach: It was entirely studied and realized chairside by a dentist on a computer, without any plaster cast or classic articulator. Vertical dimension of occlusion (VDO) augmentation was projected with the 'Incisal Tip' tool on the virtual articulator of the Cerec system. Eight composite resin overlays were designed on the non-prepared posterior teeth of a patient suffering from generalized tooth loss principally caused by a history of bulimia nervosa. The maxillary anterior teeth were restored with six palatal veneers modified with direct composites from the vestibular side, in order to improve the esthetic integration of the restorations. The mandibular posterior teeth were built up with direct composites.