This paper outlines several aspects of the integration of basic sciences into the predoctoral dental curriculum. It addresses a number of the points or questions posed by the organizers of the Third Educational Conference to Develop the Curriculum in Temporomandibular Disorders and Orofacial Pain. The importance of the basic sciences for a comprehensive overview of knowledge bearing on temporomandibular disorders and orofacial pain is first emphasized, followed by considerations of what material should be taught and by whom. The paper concludes by considering at what stage of the curriculum this material should be included, how the pertinent basics sciences should be taught, and under what circumstances. Under the term "basic sciences" are included not only relevant biomedical or biologic sciences such as physiology and anatomy, but also the behavioral sciences such as psychology and cognitive science. Keywords: biological sciences, behavioral sciences, curriculum, dentistry, temporomandibular disorders, orofacial pain, continuing education