Pain related limitations in activities of daily living are for 272 patients reporting orofacial pain of the temporomandibular region using the seven-item Pain Disability Index. Results showed that the factor structure for orofacial pain patients differed little from the factor structure for outpatients visiting chronic pain clinic settings. Analysis of pain diagnostic subgroups showed that patients suffering myogenous complaints had higher scores for four of seven daily-living activities that involved pain-related limitations than patients suffering discal disorders. The factor analytical findings indicated that these patients share common pain-related limitations in activities of daily living. These findings are also consistent with previous results indicating greater pain in orofacial pain patients diagnosed with pain complaints primarily myogenous in origin than in pain patients having discal disorders.