Microtensile bond strengths of In-Ceram Alumina cores veneered with two ceramics after different numbers of firing cycles were evaluated. After In-Ceram Alumina cores were fabricated, they were veneered with either Vitadur Alpha or Vita VM7. A control group of each core-veneer combination was fired twice, and a second group was fired five times to induce thermal fatigue. Obtained microbars were subjected to microtensile bond strength tests. Data were analyzed using two-way analysis of variance. Microtensile bond strength values for Vita VM7 specimens were higher than those for Vitadur Alpha (P .001). Although the number of firing cycles revealed no change in bond strength, the veneering material proved to be an important factor.