Purpose: The aim of this study was to assess and compare clinical outcome results of tooth-implant-supported fixed and removable partial dentures in a selected population group of partially edentulous patients. Biological and technical complications were recorded and reviewed. Materials and Methods: A retrospective analysis of the dental charts of 224 patients (174 men, 50 women) with a mean age of 51.3 years was carried out. The evaluation included details regarding the survival and technical complications of the prescribed prostheses, as well as the biological and technical complications associated with both types of abutments used, ie, teeth and implants. Results: A total of 229 prostheses were supported by 459 implants and 449 teeth. They were monitored for a period of 2 to 10 years (median follow-up time: 6.7 years). At the end of the different observation periods, 14% of the tooth-implant-supported prostheses had undergone technical modifications, with no statistical difference in the occurrence of technical complications between the 2 types of prosthesis. Three of the functionally loaded implants were removed, while 23 abutment teeth were lost (15 had undergone endodontic treatment). Abutment teeth with a reduced attachment level after prosthesis insertion were significantly affected by biological complications (P = .04). Conclusions: The survival data for both types of prosthesis were comparable to prostheses supported solely by implants. There was no difference in the complication rate between primary splinting (fixed) and secondary splinting with telescopic systems (removable). A greater risk of biological complications was recorded for endodontically treated abutments or teeth with a reduced attachment level.