The multiple loss of primary molars due to caries or other reasons in the primary or mixed dentition can lead to severe mutilation of the developing dentition. It is advisable to construct a removable appliance to maintain the relationship of the remaining teeth and to guide the eruption of the developing teeth in order to prevent the child from developing psychological and speech problems. However, parental and patient cooperation are imperative if the pediatric patient is to exercise the necessary care to maintain the denture in a clean and healthy condition. This case report identifies the complications that can arise from the uncontrolled misuse of a pediatric denture. It is concluded that as well as the parents, the pediatric dentists play an important role in the follow-up of the young patients for whom pediatric dentures are constructed. Additionally, patients should be re-called for check-up visits or instructed to refer to the dental clinics in 6-month intervals. Brochures that inform the patients and their parents about the application and care of pediatric dentures and space maintainers should be given. Keywords: pediatric denture, complication