Case description: We present 4 clinical cases with calcifications in the upper anterior teeth and their follow-up, where the clinical pictures of the cases were different. Color change, bone lesions or iatrogenic problems were the reasons for performing the RCT in the clinical cases presented. In all of them, magnification was used through the operative optical microscope. Ultrasound tips were used to access the canal at various levels in the root and after being located with manual K files 08 and 10, permeabilization was performed. They were later instrumented with MTwo rotary files and filled with thermoplastic techniques. Discussion: Calcified radicular root canals are usually a clinical challenge. Alongside calcifications, there may be other complications. The treatment of a calcified canal with no other pathologies is not consensual in the literature. The clinician should be aware of the degree of difficulty of the case and have the technical and technological ability to decide how to treat involving the patient in the decision, as some adversities may happen to even the most experienced. Conclusions: The endodontics of this type of teeth should be well evaluated and the clinician should be aware of what they can do, as this type of treatment is very demanding and can lead to iatrogenic problems. At the clinical level, objectives were met and problems resolved, as shown in follow-ups. Keywords: root canal obliteration, root canal treatment, operative optical microscope, magnification