Structure design examinations of 3-dimensional textile scaffolds using for tissue engineering in vitro

The apical growth of epithelium is a common complication following surgical parodontal therapy. Absorbable and non-absorbable membranes have been used over the last three decades as mechanical barriers to this undesired epithelial growth. Textile scaffolds seem all the more applicable, in that they allow for the local regeneration of lost tissue when colonized with autologous cells. The aim of this study was to examine the proliferation behaviour of human gingival fibroblasts on poly glycolide (PGA) fleece samples of various thickness and porosity. The fleece samples were produced in cooperation with the Institute for Textile Technology (ITA) RWTH Aachen. Keywords: tissue engineering, polyglycolide acid, human gingival fibroblasts, cell culture