Replantation is widely accepted as an effective treatment option for an avulsed tooth. However, the long-term fate of replanted teeth is unpredictable; it is dependent on various factors such as the time interval between avulsion and replantation, the storage method of teeth during the extra-alveolar period (dry storage or storage media), the vitality status of pulp or periodontal tissues, and the type and period of splinting. The appropriate use of storage media is an important clinical factor affecting the postoperative prognosis of avulsed teeth following replantation. Hanks Balanced Salt Solution (HBSS) or chilled milk are considered to be the most appropriate and clinically recommended storage media for avulsed teeth. The present review discusses the various available storage media for avulsed teeth and their potential maintenance of the vitality of periodontal ligament cells. A brief overview of the effect of clinical factors such as the storage time and temperature, and the osmolarity of storage media on their efficacy is included. Keywords: chilled milk, hanks balanced salt solution, periodontal ligament, propolis, storage media, ViaSpan