Periodontal defects in adolescents or young adults are often an incidental finding within an orthodontic treatment. Most of these patients suffer from a special form of periodontal disease: juvenile periodontitis. Guided tissue regeneration offers a technique for long-term therapy in such cases. In the case presented in this report, periodontal problems were aggravated by malpositioning of the affected teeth. Orthodontic and periodontal treatment enabled the correction of malpositioning and regeneration of osseous defects.