The influence of four denture adhesives (Fittydent, Super Poligrip, Super Wernet's, and tragacanth) on patients' opinions of 10 aspects of denture use was studied. The adhesives were applied in turn to the existing complete dentures of 32 patients in a sequence determined by eight randomly chosen 4 x 4 Latin squares of different treatments. Subjective views of the patients indicated that one product significantly improved denture retention and had other favorable features.