Pages 415-419, Language: EnglishJohnsson, Kristina / Hansson, Åse / Granström, Gösta / Jacobsson, Magnus / Turesson, lngelaThis study investigated the influence of a single 15-Gy dose of irradiation on the capacity of titanium screws to integrate in irradiated bone tissue. The biomechanical force necessary to unscrew the titanium implants 8 weeks after placement was 54% lower for implants in irradiated bone tissue compared to implants in nonirradiated bone tissue. Postirradiation use of hyperbaric oxygen treatment at 2.8 ATA (2-hour daily treatments for 21 days) increased the biomechanical force necessary to unscrew the titanium implants by 44% in irradiated bone and by 22% in nonirradiated bone.
Keywords: hyperbaric oxygen, implant interface, irradiation, osseointegration, titanium implants
