The simultaneous use of autogenous bone grafts and osseointegrated implants has opened up new possibilities in the reconstruction of large tissue defects in the oral-maxillofacial region. In this paper, the successful rehabilitation of a patient who lost the premaxilla following a segmental osteotomy is described. The resulting oronasal communication and bony defect were restored by placing a bone graft from the iliac crest that was stabilized with two osseointegrated implants. A fixed prosthesis was fabricated to replace the missing anterior teeth. Esthetic and functional criteria were fulfilled. Keywords: autologous graft, osseointegrated implants, premaxillary necrosis