Purpose: To determine whether digital training improves conceptual skills acquisition for custom tray fabrication and tooth arrangement in the preclinical curriculum for complete denture fabrication. Materialsand Methods: A crossover design study compared third-year student grades after conventional (manual) and digital training. Half the students were trained with conventional techniques prior to digital, while the other half were trained with digital techniques prior to conventional. The first part of the study (DP1) focused on custom tray fabrication and involved 154 students. The second part (DP2) focused on tooth arrangement with 204 students. The effect of preliminary digital training on conceptual skills was assessed by comparing the results of the students using Student t test. Results were also analyzed by ranking the students’ Perceptual Ability Test (PAT) score. Finally, students’ satisfaction with the training was investigated. Results: Students who completed the initial digital session achieved better custom tray fabrication and tooth arrangement in the subsequent manual sessions. For manual laboratory work, the most dexterous students (PAT1 group) demonstrated the best performance. However, PAT2 students had the best performance during the digital sessions during DP1, and PAT1 and PAT2 students had the best performance during the digital sessions during DP2. Additionally, 40% of DP1 and 12% of DP2 students expressed satisfaction with digital sessions. Conclusions: With complementary manual and digital teaching, digital tools may be useful for enhanced student learning. Digital training has contributed to improved results in manual sessions but did not affect student satisfaction and remained a limited tool to detect learning difficulties.