Actinic cheilitis of the lower lip is more common in sun-exposed regions of skin, with a malignant potential turning the lesion into epithelial cell cancer. Harmful UVB rays are a predominant cause for this potentially malignant disorder. Melanin is considered to protect the basal layer of keratinocytes, and persons with reduced melanin have a higher risk to develop actinic lesions. The patient most often goes misdiagnosed or negligence of the lesion over time will increases the risk. A case report of a patient with histopathologically confirmed actinic cheilitis diagnosed early and managed with a nonsurgical treatment approach and regular follow up of the lesion resulting in a reduction in lesion size, ulcer and burning sensation is presented herewith. Management depends on the duration, lesion size, and severity of the condition. Clinical suspicion must always be maintained in case of ulceration and nodularity.
Keywords: Actinic cheilitis, chronic sun exposure, premalignant disorder, melanin, ultraviolet rays
