Quintessence International, 6/2024
DOI: 10.3290/j.qi.b5531257, PubMed ID (PMID): 38949791Pages 428, Language: EnglishEliav, EliEditorialQuintessence International, 3/2024
DOI: 10.3290/j.qi.b5143075, PubMed ID (PMID): 38534033Pages 176-177, Language: EnglishNahlieli, Oded / Eliav, EliEditorialQuintessence International, 3/2024
DOI: 10.3290/j.qi.b5143737, PubMed ID (PMID): 38536123Pages 177-178, Language: EnglishUlrich, Ina B. / Eliav, EliEditorialQuintessence International, 2/2024
DOI: 10.3290/j.qi.b5031229, PubMed ID (PMID): 38414367Pages 88-89, Language: EnglishArany, Szilvia / Caprio, Thomas V. / Medina-Walpole, Annette / Eliav, EliQuintessence International, 1/2024
DOI: 10.3290/j.qi.b4893093, PubMed ID (PMID): 38259031Pages 2-3, Language: EnglishBiron, Adi / Eliav, Eli / McNeil, RotemEditorialQuintessence International, 5/2023
DOI: 10.3290/j.qi.b4105017, PubMed ID (PMID): 37204104Pages 356-357, Language: EnglishEliav, Eli / Levin, LiranEditorialQuintessence International, 2/2023
DOI: 10.3290/j.qi.b3879801, PubMed ID (PMID): 36762850Pages 90-91, Language: EnglishTeich, Sorin / Eliav, EliEditorialJournal of Oral & Facial Pain and Headache, 2/2023
DOI: 10.11607/ofph.2023.2.ePages 77-78, Language: EnglishEliav, Eli / Arany, SzilviaEditorialQuintessence International, 1/2023
DOI: 10.3290/j.qi.b3803631, PubMed ID (PMID): 36637261Pages 4, Language: EnglishEliav, EliEditorialJournal of Oral & Facial Pain and Headache, 1/2022
DOI: 10.11607/ofph.3050Pages 67-77, Language: EnglishOzasa, Kana / Noma, Noboru / Kobayashi, Momoyo / Takizawa, Keita / Young, Andrew / Eliav, Eli / Imamura, Yoshiki
Aims: To investigate the predictive power of depression and anxiety for conditioned pain modulation (CPM) and to examine the relationships of CPM at 40°C and CPM at 47°C with age, disease-related pain, pain duration, and psychosocial factors in burning mouth syndrome (BMS).
Methods: A total of 22 patients with BMS and 22 healthy female controls participated in this study. Temporal summation was used as the test stimulus for CPM, and subsequent exposure either to a nonpainful (40°C) or a painful (47°C) Peltier thermode was used as the conditioning stimulus. CPM was calculated as the difference in pain perception following the conditioning stimulus. Psychosocial factors were examined using the Profile of Mood States (POMS) and the State-Trait Anxiety Inventory (STAI).
Results: State anxiety and tension-anxiety scores were significantly higher for patients with BMS than for control participants. Multiple regression analyses showed that CPM47°C was affected by vigor, fatigue, confusion, and trait anxiety (adjusted R2 = 0.685, F = 5.147, P = .098). The corresponding analysis for CPM40°C showed that the model was not predictive for the following variables: disease-related pain, pain duration, or components of the POMS or STAI. A significant positive correlation was found between CPM47°C and trait anxiety, suggesting that trait anxiety negatively affected the endogenous pain modulation system.
Conclusion: Increases in trait anxiety reduced the CPM effect. These findings suggest that CPM impairments and increases in trait anxiety are involved in the development of BMS.
Keywords: anxiety, burning mouth syndrome, conditioned pain modulation, depression, state-trait anxiety inventory
