This study evaluated the concept of computer-aided design of anterior teeth by integrating morphologic information about the mirrored contralateral teeth. With the aid of a digital 3-dimensional tooth library, ipsilateral teeth were automatically mirrored, rotated, and translated to fit in the locations of the contralateral teeth. The reconstruction outcomes were evaluated via 3-dimensional similarity measures, measurements of approximal and antagonistic relationships, and visual ratings of experts. Metric and visual judgments indicate that integrating the shape of a symmetrically located contralateral anterior tooth seems to be a suitable base concept for computer-aided design of anterior restorations.