Thirteen irradiated and 14 nonirradiated patients were treated after resection of a malignant oral lesion. With a follow-up period of 26 months, 3 of 48 implants in nonirradiated patients and 4 of 57 implants in irradiated patients failed. In comparison to implant-tissue-supported prostheses, exclusively implant-supported prostheses demonstrated better results with regard to soft tissue trauma and function of the prosthesis. Schlagwörter: dental implant, oral malignancy, Procera technique, prosthetic implantology, radiation, surgical implantology