Whether the result of technical errors or anatomic aberrations, malalignment of osseointegrated implants can create significant difficulty for the restorative dentist who fabricates the final tissue-integrated prosthesis. As a result, the planned prosthesis may defy completion or the implants may have to be left buried. This clinical report illustrates a solution to fabricating a fixed/detachable tissue-integrated prosthesis on malaligned posterior mandibular implants. Keywords: implants, malalignment, partial edentulism