Corticocancellous iliac bone grafts are used to restore mandibular continuity following trauma or tumor ablative surgery. Secondary placement of titanium osseointegrated implants in these bone grafts allows for precise and predictable prosthodontic rehabilitation with a bone-supported prosthesis. This two-stage surgical-prosthetic reconstruction has been accomplished for five patients at the Mayo Clinic. A general review of this series and a detailed presentation of three patients, with follow-up, is provided. Keywords: dental implants, mandibular discontinuity, mandibular reconstruction, oral prosthetic reconstruction