The clinical requirements that led to the development of the new ITI implant concept are discussed. This concept consists of a system of one- and two-part hollow-cylinder and hollow-screw implants and is characterized by a wide range of indications. The one-part implants are intended for use in edentulous mandibles as retentive anchors for bar type overdenture reconstruction. The two-part implants are intended for use in partially edentulous jaws as abutments for fixed prosthesis reconstructions. The clinical aspects of the new ITI implants are discussed and documented by case examples and early clinical results. Keywords: fixed prosthesis, hollow-cylinder implants, hollow-screw implants, ITI implants, osseointegration, overdenture