Dengue infection is one of the most common mosquito-borne viral diseases of humans worldwide, representing a significant public health problem in over 100 tropical countries where its primary vector Aedes aegypti occurs. Although the disease is frequently limited to an abrupt febrile illness, it may also cause significant morbidity and if not adequately treated, mortality. Therefore, it requires a correct and early diagnosis. Oral manifestations of dengue infection are commonly reported as gingival bleeding, but detailed description of oral alterations in the context of dengue infection is lacking in the literature. Thus, in the current manuscript the authors aimed to report a case of dengue viral infection in an 18-year-old male patient who was primarily diagnosed due to extensive oral involvement characterized by the presence of gingival and lip reddish swelling, highlighting the importance of an adequate oral evaluation of patients with symptoms suggestive of dengue, especially in known endemic regions. Keywords: Aedes aegypti, dengue fever, dengue virus, oral cavity