The integration of modern technologies in removable prosthodontics in terms of complete denture fabrication has revolutionized fabrication procedures, improved outcomes, and led to advancements in denture materials. Numerous publications have described the digital techniques of complete denture fabrication. The steps described in these publications for the proposed digital workflow are diverse. This is suggestive of the flexibility of these modern techniques in terms of their integration with the steps of conventional protocols. Automated technologies have reduced the need for skilled manual work, while particular knowledge and a new skills set are required for both clinicians and dental technicians. Moreover, the effectiveness and efficacy of these modern technologies in complete denture fabrication are yet to be determined. To consolidate the existing literature on digital techniques of complete denture fabrication, this review summarizes the current digital workflows of the clinical and laboratory stages, describes the digital alternatives in each step, and discusses their advantages and limitations.