Trombelli, Leonardo

Background: SPAL technique in combination with a xenograft has been successfully used to correct a peri-implant bone dehiscence (PIBD) and increase peri-implant buccal tissue thickness. The purpose of the present study was to determine the histological nature of the newly formed tissue at sites treated using SPAL in association with particulate deproteinized bovine bone mineral (pDBBM). Methods: 6 patients were consecutively selected for treatment with the SPAL technique combined with pDBBM. At 6-month re-entry, samples were harvested from the areas included in the bone augmentation procedure for histological qualitative and quantitative analysis. Results: Well organized newly formed bone was present in close contact with the residual graft in all patients. However, a variability in the percentage of new bone was found among patients, ranging from 35.54% to 65.68%. Medullary spaces were populated by osteoblast-like cells and blood vessels running close to the residual graft and newly formed bone. No signs of pathological inflammatory infiltrate were observed. Conclusion: The histological analysis indicated that the SPAL technique leads to a variable amount of newly formed bone which showed a well-organized and mature architecture, even within a relatively short healing period, in close contact to the residual DBBM particles. Parole chiave: case-report, peri-implant bone dehiscence, lateral bone augmentation, dental implant, particulate bone, SPAL technique

Purpose: To achieve a consensus among international experts regarding the management of postoperative complications after maxillary sinus floor elevation. Materials and methods: A total of 32 experts were enrolled and divided into dental implant providers (21), experts with a well-established reputation as sinus specialists (8), ear, nose and throat specialists (2), and experts with a well-established reputation as ear, nose and throat specialists (1). Before starting, a systematic literature search was conducted on the topic, and a list of articles was sent to the panel. The development group formulated 20 statements, which were sent out in the form of a survey. After each round, the statements upon which a consensus was not reached were reformulated based on anonymous comments from participants. A total of three rounds were planned. Results: After the third round, a consensus was reached on 15 key statements regarding the management of postoperative complications following sinus floor elevation. Agreement was established on issues including common postoperative symptoms, use of radiographic assessments, the necessity of surgical interventions such as partial or total graft removal, and the potential need for functional endoscopic sinus surgery. Near-consensus was achieved on additional points concerning normal postoperative symptoms, timing of total graft removal and approaches to late graft infections. Conclusions: The present Delphi consensus suggests that postoperative symptoms such as pain and swelling are generally manageable with appropriate pharmacological treatment. It also outlines conditions where radiographic evaluation is recommended for further assessment. Surgical options, including partial or total graft removal and functional endoscopic sinus surgery, are recommended based on the clinical scenario and response to initial treatments. Variability in practices, particularly regarding antibiotic use and specific intervention timing, suggests a need for further research to be conducted in order to standardise treatment protocols and address gaps in evidence. Parole chiave: consensus, maxillary sinusitis, peri-implantitis, sinus floor augmentation The authors declare there are no conflicts of interest relating to this study.

The purpose of the present study was to describe a novel protocol for a minimally invasive pocket elimination surgery (MI-PES) in the posterior maxilla and mandible, which consists of the combined use of (1) an access flap based on an internally beveled gingivectomy with minimal to no papilla mobilization at the buccal aspect, and (2) a resective procedure with an apically positioned flap on the lingual aspect. The interproximal bone defects were accessed with a single (lingual) flap, and the bone architecture was modified by the adoption of piezoelectric inserts for controlled bone recontouring associated with fiber retention. Mean probing depth (PD) was 5.5 ± 0.8 mm before surgery and 2.7 ± 0.6 mm at the 6-month reevaluation. All treated pockets showed a postsurgical PD < 4 mm. Gingival recession (REC) was 0.3 ± 0.5 mm at baseline and increased to 1.6 ± 0.8 mm at 6 months. When buccal and lingual pockets were analyzed separately, a trend toward a similar PD reduction, less REC increase, and greater clinical attachment level gain was recorded for buccal pockets. These preliminary observations seem to support the use of MI-PES as a valuable option for pocket elimination, at least when residual pockets are associated with a shallow interproximal osseous crater in the posterior maxilla or mandible.

Purpose: To comparatively evaluate transcrestal sinus floor elevation (tSFE) and lateral sinus floor elevation (lSFE) at sites with different residual bone heights (RBHs). Materials and Methods: A re-analysis of data from a parallel-arm, randomized trial comparatively evaluating tSFE and lSFE was performed. Within each RBH interval (< 4 mm or ≥ 4 mm), tSFE and lSFE groups were compared for chair time, surgery-related costs, morbidity, and radiographic parameters (including the proportion of the implant surface in direct contact with the radiopaque area [totCON%]). Results: The intention-to-treat (ITT) population consisted of 29 and 28 patients in the tSFE and lSFE groups, respectively. Irrespective of RBH, both tSFE and lSFE lead to a median totCON% of 100%. At sites with RBH < 4 mm, pain severity was significantly higher at days 0 and 1 in the tSFE group, with no intergroup difference in the dose of analgesics. LSFE was associated with a significantly higher frequency of bruising and greater cost. At sites with RBH ≥ 4 mm, a significantly lower frequency of postoperative signs/symptoms, less chair time, and lower costs were observed in the tSFE group. Conclusions: The selection of tSFE or lSFE within the investigated RBH intervals seems to be supported by differences in chair time, costs, and morbidity between the two techniques. At sites with RBH < 4 mm, clinicians preferring tSFE should encourage the administration of analgesics according to a predefined plan in the early postoperative phase. At sites with RBH ≥ 4 mm, tSFE should be preferred to lSFE due to reduced chair time, costs, and morbidity. Parole chiave: alveolar process, bone resorption, maxillary sinus, bone regeneration, minimally invasive, dental implants

Peri-implant diseases at implant sites represent the most considerable concern for many dental clinicians nowadays due to their detrimental effect on implant longevity. Preventive measures include patient education and motivation, supportive peri-implant therapy and routine assessment of the hard and soft tissues. Nevertheless, the reliability of clinical parameters to monitor peri-implant conditions is subject to debate. As such, the primary purpose of the present review was to gain further insight into the diagnostic accuracy of probing as a clinical tool to monitor dental implants and assist clinicians in preventing peri-implant diseases. Studies have recommended periodic probing to monitor the condition of the peri-implant tissues. Increased probing pocket depth, profuse bleeding on probing and suppuration at implants are clinical signs that have been associated with peri-implantitis; thus, if these clinical parameters are present, radiographic assessment is encouraged to make a definitive diagnosis considering potential inaccuracies related to local and/or systemic factors identified in the present review. Parole chiave: complications, diagnostic procedure, peri-implantitis, surgical Conflict-of-interest statement: The authors declare there are no conflicts of interest relating to this study.

Purpose: This case series illustrates a simplified soft tissue management, namely, the subperiosteal periimplant augmented layer (SPAL), to increase hard and soft tissue dimensions at the most coronal portion of an implant. Materials and Methods: Twenty-seven implants in 16 patients presenting either a buccal bone dehiscence or a thin ( 1 mm) buccal cortical bone plate (BCBP) were consecutively treated. Briefly, a split-thickness flap (namely, the mucosal layer) was raised on the buccal aspect. Then, the periosteal layer was elevated from the bone crest. A full-thickness flap was elevated on the oral aspect. After implant site preparation, a xenograft was used to fill the space between the periosteal layer and the BCBP and/or exposed implant surface and, if present, to completely correct the bone dehiscence. The periosteal layer was sutured to the oral flap. The mucosal layer was coronally advanced and sutured to submerge both the graft and the implants. At 3 to 6 months, a re-entry procedure for implant exposure was performed. Results: Healing was uneventful, with no signs of infection in all cases. A wound dehiscence was observed in three implants in two patients at 2 weeks postsurgery. Out of 15 implants showing an initial bone dehiscence, 12 implants (80%) showed a complete resolution, with a subperiosteal tissue thickness (SPTT) at the time of re-entry of 3.1 ± 1.0 mm. Three implants presented a residual dehiscence of 1 mm (two implants) or 2 mm (one implant), with a SPTT of at least 2 mm. Out of 12 implants showing a thin BCBP at implant placement, 10 implants (90%) revealed a SPTT ≥ 2 at the time of re-entry. Two implants revealed a SPTT of 1 mm. Conclusion: The SPAL technique represents a valuable simplified surgical approach associated with a low rate of complications in the treatment of peri-implant bone dehiscence and in the horizontal augmentation of peri-implant tissue thickness. Parole chiave: alveolar bone loss, bone dehiscence, implant dentistry, reconstructive surgical procedures, surgical flaps, wound healing

The present study was performed to evaluate the impact of smoking status on 6-month clinical outcomes of a regenerative procedure based on enamel matrix derivative and deproteinized bovine bone mineral in the treatment of intraosseous defects accessed with buccal single flap approach. A total of 22 defects were selected in smoking (n = 11) and nonsmoking (n = 11) patients. Regenerative treatment resulted in similar clinical attachment level (CAL) gain in both smokers and nonsmokers. A trend toward lower 6-month CAL gain and probing depth reduction was observed in patients smoking 11 to 20 cigarettes per day compared to those smoking 1 to 10 cigarettes per day.

Purpose: Implant-supported mandibular overdentures (OVDs) have been proposed as the gold standard for the treatment of edentulous mandibles. There is limited evidence on the clinical outcomes of immediate loading of two unsplinted implants supporting a mandibular OVD. The purpose of this randomized controlled trial was to evaluate the performance of two unsplinted implants supporting a Locator-retained mandibular OVD over 12 months loaded immediately or after a delay. Materials and Methods: Each patient received two implants 4.0 mm in diameter and 8 to 15 mm long. Locator-retained mandibular OVDs were connected to the implants either immediately (IL) or 3 months postsurgery (DL). The primary response variable was radiographic bone loss (RBL) at 6 and 12 months postsurgery. Implant length, insertion torque, implant failure, prevalence of maintenance visits, and prosthetic complications were also recorded. Results: Thirty participants (15 in the IL and 15 in the DL groups) were evaluated at 12 months. The implant cumulative survival rates were 100% and 93% for DL and IL, respectively. The mean RBL from baseline to 1 year was 0.54 (± 0.5) mm and 0.25 (± 0.5) mm for DL and IL, respectively. A statistically significant difference was observed at 12 months, with less RBL in the IL group. Insertion torque and implant length were not correlated with RBL. Also, no difference in frequency of maintenance visits and prosthetic complications was reported between the groups. Conclusion: Immediate loading of two unsplinted implants supporting a Locator-retained mandibular OVD seems to be a suitable treatment option. Significantly less RBL was observed after 1 year of loading around IL implants than around DL implants. Furthermore, neither implant length nor insertion torque seemed to affect RBL 1 year after surgical placement. Parole chiave: immediate loading, overdenture

Twenty-four periodontal intraosseous defects were accessed with a buccal single-flap approach (SFA) and treated with enamel matrix derivative (EMD) or EMD + deproteinized bovine bone mineral (DBBM) according to the surgeon's discretion. EMD with or without DBBM was clinically effective in the treatment of periodontal intraosseous defects accessed with a buccal SFA. The adjunctive use of DBBM in predominantly onewall defects seemed to compensate for, at least in part, the unfavorable osseous characteristics in terms of the outcomes of the procedure.

Zielsetzung: Untersuchung der Prävalenz und Verteilung von Sondierungsbluten (BOP = bleeding on probing) bei Patienten mit Parodontopathien. Untersuchung des Einflusses von patientenbezogenen Parametern auf die individuelle Variabilität von BOP. Beschreibung von zwei Teilgruppen von Patienten mit signifikant unterschiedlichem BOP-Wert. Material und Methode: 601 Patienten wurden in die retrospektive Untersuchung einbezogen. Der Prozentanteil der Messpunkte mit BOP wurde für das Gesamtgebiss (%BOPtotal), wie für verschiedene Unterbereiche des Gebisses berechnet. Außerdem wurde der mögliche Einfluss von patientenbezogenen Faktoren auf die interindividuelle Variabilität von %BOPtotal bewertet. Es wurden zwei Teilgruppen von Patienten mit geringem beziehungsweise starkem Sondierungsbluten, also niedrigem beziehungsweise hohem Median für %BOPtotal, definiert (unteres und oberes Quartil). Ergebnisse: Der Median für %BOPtotal lag bei 26,4 %. 99 % der Studienpopulation wiesen mindestens eine Messstelle mit BOP auf. Für %BOPtotal gab es positive Korrelationen mit dem Alter der Patienten und mit einer Sondierungstiefe (ST) >= 5 mm; BOP trat signifikant häufiger bei Messpunkten im Unter- als im Oberkiefer, im Seiten- als im Frontzahnbereich, an interproximalen als an oralen/bukkalen Messstellen sowie an Messstellen mit ST >= 5 mm gegenüber solchen mit ST = 4 mm auf. Patienten mit geringem und mit starkem Sondierungsbluten unterschieden sich signifikant hinsichtlich %BOPtotal und BOP bei Messpunkten mit ST = 4 und ST >= 5 mm, jedoch nicht hinsichtlich Geschlecht, Nikotinstatus, Zigarettenkonsum, Diabetes oder Messpunkten mit ST >= 5 mm. Schlussfolgerungen: Die Prävalenz und Variabilität von BOP war von Patient zu Patient und von Kieferbereich zu Kieferbereich hoch. Patienten- und ortsspezifische Faktoren (Alter, Zahl der Parodontaltaschen, Sondierungstiefe, Zahntyp, relative Position der Messpunkte) scheinen für die Variabilität von BOP teilweise mitverantwortlich zu sein. Patienten mit geringem und mit starkem BOP unterschieden sich nicht signifikant hinsichtlich der untersuchten Parameter mit potenziellem Vorhersagewert. Parole chiave: Sondierungsbluten, Gingivitis, Parodontopathie