Fibrohistiocytic Tumors of the Oral cavity - A way to go about

Fibrohistiocytic neoplasms are a diverse group of tumors that exhibit fibroblastic and histiocytic differentiation. The biphasic cell population is believed to arise from histiocytes. Though oral lesions are rare, Benign fibrous histiocytoma frequently involves buccal mucosa and vestibule. The important diagnostic distinction is the separation of the benign tumor from malignant fibrous histiocytoma, a high grade sarcoma commonly involving maxillary region & sinonasal tract and other aggressive forms of histiocytic lesions. The diagnosis frequently relies upon immunohistochemistry. The histologic features play a minor role in prediction of the biologic behaviour of these neoplasms. The aim of this poster is to present the histiocytic neoplasms reported in our institution and to discuss the main diagnostic criteria of these neoplasms with immunohistochemistry markers, including the differential diagnosis to differentiate from other histiocytic lesions of the jaw. Keywords: Fibrohistiocytoma, Biphasic cell population, immunohistochemistry markers