DOI: 10.11607/prd.2170, PubMed ID (PMID): 26133146Pages 560-569, Language: EnglishNtounis, Athanasios / Pitman, Lillie M. / Pollini, Adrien / Vidal, Ricardo / Lin, Wei-Shao / Madigan, Michael P. / Greenwell, HenryThe purpose of this article is to present a surgical and restorative protocol for the replacement of missing teeth in the esthetic zone. The ABC protocol consists of digitally guided implantation, autogenous bone graft (A), followed by bovine bone xenograft (B) and connective tissue graft (C). Autogenous bone is placed in contact with the implant surface to induce osseointegration; bovine bone xenograft is then applied to augment the ridge dimension and provide long-term stability. Connective tissue is used to provide additional volume. The ABC biomaterial sequence offers favorable hard and soft tissue dimensions and immediate provisional restoration predictably leads to an esthetically pleasing definitive prosthesis.