DOI: 10.11607/ijp.3785, PubMed ID (PMID): 24392473Pages 15-25, Language: EnglishPesce, Paolo / Menini, Maria / Tealdo, Tiziano / Bevilacqua, Marco / Pera, Francesco / Pera, PaoloPurpose: This systematic review considers possible etiologic factors and definitions of peri-implantitis as reported in the recent literature.
Materials and Methods: An electronic search of databases plus a hand search of the most relevant journals published between January 2005 and September 2012 were performed.
Results: The electronic and manual searches yielded 640 and 14 titles, respectively. From the independent doublecheck of the titles and abstracts, 24 full texts were downloaded (18 clinical studies and 6 animal studies). After reading the full texts, 10 articles (4 clinical studies and 6 animal studies) were included in this review. None of the human articles selected provided sufficient evidence to address the research question, and no human clinical evidence is available to support a cause-effect relationship between peri-implantitis and bacterial accumulation and/or occlusal overload. The animal literature is also not unanimous regarding a specific peri-implantitis etiology. However, a correlation between periodontitis and smoking histories was cited as contributing to a higher incidence of peri-implantitis.
Conclusion: The available scientific literature is characterized by an absence of a unanimous consensus regarding the etiology of peri-implantitis and its specific relationship to periodontitis. Furthermore, both the choice of the term peri-implantitis and its definition remain controversial. Int J Prosthodont 2014;27:15-25. doi: 10.11607/ijp.3785
