Failure rates of traditional fixed partial dentures, resin-bonded prostheses, and implant restorations for the replacement of a single missing tooth are compared in this literature review. A lack of documented longevity studies involving conventional fixed partial dentures makes failure rates difficult to determine. Reported failures ranged from only 3% over 23 years to 20% over 3 years. The major causes of loss were caries and endodontically and periodontally related complications. Research concerning resin-bonded fixed partial dentures was more prevalent, but indicated that overall retention of these prostheses may be unpredictable. Failure rates were quite divergent, ranging from 10% over 11 years to 54% over 11 months. Debonding was the usual cause of failure. Clinical reports of single-tooth implant replacements have followed stricter protocols than the other two alternatives. Short-term studies indicated favorable success rates for these restorations, but these must be confirmed by long-term evaluations. Failures ranged from 9% over 3 years to 0% over 6.6 years. These comparisons should be considered in treatment planning a restoration for the replacement of a single missing tooth.