Objectives: The aim of this study was to evaluate tensile bond strength of six different dentin adhesives (Excite, Admira Bond, Clearfil New Bond, AdheSE, Xeno III, Syntac) combined with the corresponding composite material on perfused dentin in vitro. Methods: Ninety freshly extracted molars, stored in saline for a maximum of fourteen days after extraction were included. All teeth were specially prepared allowing the simulation of dentin perfusion. Dentin specimens with a total thickness of 3.5 mm were obtained under standardized conditions. The specimens were randomly assigned to six experimental groups of fifteen samples each: Group A: Excite/ Tetric; group B: Admira Bond/ Admira; group C: Clearfil New Bond/ Clearfil Core; group D: AdheSE/ Tetric; group E: Xeno III/ Esthet X; group F: Syntac/ Tetric. Tensile bond strength was measured 15 minutes after application and light curing of the composite material (colour A2) using an universal testing machine. Results: For the six test series following tensile bond strengths were evaluated (mean value and standard deviation in MPa): group A: 4.74 (± 1.81), group B: 4.62 (± 1.21), group C: 4.68 (± 1.04), group D: 2.59 (± 0.79), group E: 6.90 (± 1.33); group F: 3.87 (± 0.94). Statistical analysis showed a significant influence of the used material combination on tensile bond strength (p Palabras clave: bond strength, adhesives, perfused dentin