Introduction: The innervation of the hard and soft tissues of the maxillary anterior area depends on the nasopalatine nerve. Due to its anatomy and closeness to implants in the esthetic area, it is essential to fully comprehend its traits and possible effects while performing implant placement procedures. Objective: To assess the prevalence of neurosensorial alteration and the survival and success rate of dental implants in a relationship with the nasopalatine canal. Material and methods: A comprehensive search of the literature was conducted in the following databases: MEDLINE, Web of Science, and Scopus. The articles included had to be case series, studies conducted in patients undergoing dental implant procedures in the incisive canal region or undergone dental implant procedures with incisive canal deflation or neurovascular lateralization. A quantitative synthesis using a meta-analysis software program was performed. Fixed- or random-effect models were applied based on the heterogeneity among studies. Results: Four studies were included. Neurosensorial alterations were presented in three out of four articles included. The range of neurosensorial alterations varied from 30% to 60%. A weighted mean of 29 % ± 13 % of neurosensorial alterations was calculated from the meta-analysis meanwhile a mean of 100 % of implant survival and 100% of implant success were found. In the results, please clarify that "29%±13%" represents the weighted mean calculated from the metaanalysis. Conclusions: Implants in the nasopalatine area are associated with high rates of survival and success being a safe procedure, however, clinicians should be aware that neurosensorial alterations may be present when placing implants in this area.
