Purpose: To investigate how well an implant stability quotient (ISQ) represents resonance frequency. Materials and Methods: Benchtop experiments on standardized samples that replicated a mandibular premolar site were conducted to correlate an ISQ value and a resonance frequency to synthetic bone density and an incremental insertion torque; then, a frequency spectrum analysis was performed to check the validity of the resonance frequency analysis (RFA). Brånemark Mk III implants (4 × 11.5 mm; Nobel Biocare) were placed in Sawbones test models of five different densities (40, 30, 40/20, 20, and 15 PCF). An incremental insertion torque was recorded during implant placement. To perform stability measurements, the test models were partially clamped in a vise (unclamped volume: 10 × 20 × 34 mm). A MulTipeg (Integration Diagnostics) was attached to the implants, and a Penguin (Integration Diagnostics) RFA measured ISQ. Simultaneously, the MulTipeg motion was monitored via a laser Doppler vibrometer and processed by a spectrum analyzer to obtain the resonance frequency. Tightness of the clamp was adjusted to vary the resonance frequency. A statistical analysis produced a linear correlation coefficient (R) among the measured ISQ, resonance frequency, and incremental insertion torque. Results: The resonance frequency had high correlation to the incremental insertion torque (R = 0.978), confirming the validity of using RFA for this study. Measured ISQ data were scattered and had low correlation to the resonance frequency (R = 0.214) and the incremental insertion torque (R = 0.386). The spectrum analysis revealed the simultaneous presence of multiple resonance frequencies. Conclusions: For the designed benchtop tests, resonance frequency does indicate implant stability in view of Sawbones density and incremental insertion torque. However, ISQ measurements do not correlate to the resonance frequency and may not reflect the stability when multiple resonance frequencies are present simultaneously.