Purpose:To evaluate the masticatory efficiency of dentate and rehabilitated complete denture patients in various facial forms. Materials and Methods: A total of 60 subjects were selected for the study; 30 subjects belonged to the dentate group (D Group) and 30 subjects belonged to the completely edentulous group rehabilitated with conventional complete dentures (CECD Group). All patients were divided into a subgroup (brachyfacial, mesofacial, and dolichofacial facial forms) using facial index measurement and cephalometric analysis. After the subjects were divided into groups, masticatory efficiency testing was performed with spectrophotometric analysis using diluted expectorate of chewed natural beetroot test food (10, 15, and 20 strokes). The mean absorbance value was considered as the mean masticatory efficiency from which the average masticatory efficiency percentage was determined using a masticatory efficiency percentage equation and considered as the masticatory efficiency of that particular subject. Results: Statistical analysis revealed that in the D Group, brachyfacial subjects exhibited the highest masticatory efficiency (70.9 ± 12.64%), followed by mesofacial (60.6% ± 10.66%) and dolichofacial (34.3% ± 10.81%) subjects. In the CECD groups, the results for brachyfacial were highest (52.7% ± 8.11%), followed by the mesofacial (42.3% ± 6.52%), and dolichofacial (29.3% ± 7.76%) subjects. Conclusions: Along with other determinant factors, facial form plays an influential role on masticatory efficiency. Brachyfacial subjects exhibited the highest masticatory efficiency, followed by mesofacial and dolichofacial subjects in both study groups.