The latest version of the Biotech Dental Smilers planification software allows the linking of information from STL files provided by optical oral scans (or digital scanning, following traditional impressions) and information from DICOM files provided by cone beam computed tomography (CBCT). These three-dimensional (3D) elements can also be coupled with two-dimensional (2D) photographs of the patient in order to add more options. The new radicular and bone segmentation option obtained thanks to information from DICOM files heralds a new era of orthodontics. From now on, multi-layer 3D information can be accessed, which opens up a new field of possibilities for bodily translation movement and torque control. Moreover, tooth root axes and occlusal plane evaluations that were a common source of error with aligners and digital planning are more reliable. 2D mock-ups with photomorphing can be presented to patients, and global multidisciplinary 3D-assisted treatment plans on a single common platform will help practitioners in their everyday practice, with less chairside work and more visibility. Access to this information will provide better simulation and predictability of tooth movement, for increased accuracy and improved results. Keywords: CBCT, Class II, DICOM, implant, missing lateral incisor, root segmenting, Smilers, torque, translation Conflict of interest statement: Dr Arash Zarrinpour is an inventor and international speaker for Biotech Dental Smilers.