Poster 2086, Language: EnglishGuedes, Manuel Pedro Pacheco Moreira / Milheiro, F. / Pires-Gonçalves, C. / Rolo, D. / Reis, J. / Figueiredo Dias, A.Introduction: It is estimated that only 1% of the malignant tumours that affect the oral cavity occur due to primary neoplasms of another location and of these, about 1% originate in thyroid tumours. Papillary thyroid carcinoma (PTC) is the most common and well-differentiated cancer of the thyroid, accounting for 80-90% of the total malignancies that affect this gland. Metastisation occurs mainly to the regional lymph nodes, with the occurrence of jaw metastases being exceptionally rare. Metastases that occur in the oral cavity seem to exhibit a predilection for mandibular body and angle, which seems to reflect the rich vascularisation of the medullary space of these regions.
Case description: We report a case of a 70-year-old female patient with a history of PTC who, after adequate observation and diagnostic orientation, revealed a rare occurrence of mandibular PTC metastasis. A brief review of the literature will be made regarding clinical presentation, radiological aspects, and treatment options. Discussion/
Conclusions: Metastatic PTC to the mandible is a rare event; however, the possibility of its occurrence must be established when the differential diagnosis of maxillofacial tumours is performed. Despite the relatively indolent behaviour of this thyroid neoplasm and its good survival when suitably treated at baseline (~ 95%), the prognosis of patients with distant metastatic disease declines considerably, with only 40% of patients alive 4 years after diagnosis. Thus, timely detection of metastatic disease and its therapeutic orientation has an invaluable impact on the overall survival rate.
Keywords: papillary thyroid carcinoma, jaw metastasis
