Function and esthetics are very important for all kinds of dental restorations. For a fixed implant restoration, the positions of the implants and the emergence profiles are very important to have a good result. CAD-CAM systems help us for planning, as well as preparing the guide for guided surgery and fabricating the final restoration. Digital Workflow for a monolithic zirconia bridge on six iSy implants is presented in this case report. Keywords: Implant, isy, camlog, guided surgery, cerec, cerec guide, tibase, monolithic zirconia, full arch, bridge