Purpose: To evaluate the biomechanical behavior of implants with different neck designs. Materials and Methods: Finite element models of implants with two different neck designs (OsseoSpeed EV and OsseoSpeed Profile EV) were generated. Implants and abutments were subjected to buccally and lingually directed 30-degree oblique loads of 200 N. Results: Under buccally angulated load, the Profile implant model showed lower minimum principal stress when compared to the standard implant model (-63.4 vs -91.9 MPa), whereas the von Mises stress value of the Profile implant model was higher (342 MPa). Conclusion: This preliminary study showed that Profile implants placed in alveolar ridges with buccolingual bone height discrepancy showed similar stress distribution and stress value outcomes when compared to standard implants.