The aim of this study was to evaluate stress patterns at the bone-implant interface of tilted versus nontilted implant configurations in edentulous maxillae using finite element models of two tilted and one nontilted configuration. Analysis predicted the maximum absolute value of principal compressive stress near the cervical area of the distal implant for all models. The tilted configurations showed a lower absolute value of compressive stress compared with the nontilted, indicating a possible biomechanical advantage in reducing stresses at the bone-implant interface.