Objective: To describe an innovative endoscopic technique for root canal treatment. Materials and Methods: Root canal treatment was performed on 12 patients (15 teeth), using a newly developed endoscope (Sialotechnology), which combines an endoscope, irrigation, and a surgical microinstrument channel. Results: Endoscopic root canal treatment of all 15 teeth was successful with complete resolution of all symptoms (6-month follow-up). Conclusion: The novel endoscope used in this study accurately identified all microstructures and simplified root canal treatment. The endoscope may be considered for use not only for preoperative observation and diagnosis but also for active endodontic treatment. Keywords: endoscope, root canal treatment