The current S2k-Guideline of the DEGRO (German Society for Radiation Oncology) provides a "should" recommendation for gonarthritis and a "can" recommendation for other arthritides. Thus, according to the guideline's recommendations, there is also the possibility to employ irradiation in the treatment of osteoarthritis or degenerative and/or inflammatory arthropathies of the TMJ. Keywords: activated osteoarthritis, degenerative arthropathy, radiotherapy, symptomatic inflammatory arthropahy, temporomandibular joint, treatment option