Odontogenic myxoma is a rare intraosseous neoplasm that is benign but locally aggressive. It rarely appears in any bone other than the jaws. It is considered to be derived from the mesenchymal portion of the tooth germ. Clinically, it is a slow-growing, expansile, painless, tumour of the jaws, chiefly the mandible. Here we report the case of an odontogenic myxoma in a 20-year-old male patient, which had acquired large dimensions and involved the entire mandible including the ramus, resulting in a gross facial asymmetry and swelling within a span of six months. No history of trauma and relevant dental and systemic history were present.
The diagnosis consists of clinical findings along with a radiographic study including orthopantomogram, cone beam computed tomography, and computed tomography, but which has been confirmed by histologic analysis; proper histopathological diagnosis is required for efficient management. Radiographic features showed multilocular radiolucency with a tennis racket pattern with cortical plate expansion. The treatment of odontogenic myxoma is primarily surgical and varies from simple enucleation and curettage to more extensive radical surgery. Long-term follow-up is required due to the high risk of recurrence.