The International Journal of Oral & Maxillofacial Implants, Pre-Print
DOI: 10.11607/jomi.10803, PubMed-ID: 3839444023. Feb. 2024,Sprache: EnglischOhayon, Laurent / del Fabbro, MassimoPurpose: Maxillary sinus floor augmentation is a safe and predictable technique used to increase
bone volume under sinus cavity for implant placement in atrophic posterior maxilla before
implant placement. Despite conflicting results concerning the new bone formation rates with or
without a barrier membrane, the benefits of using a collagen membrane to cover the lateral bone
window has been demonstrated, in order to prevent bone substitute particles dislodgement that
may occur from the sinus cavity through the sinus antrostomy towards the oral mucosa, and to
significantly reduce the postoperative swelling and pain reactions. The purpose of this case series
is to present a sling suture technique used to stabilize the collagen membrane against the lateral
bone window so as to improve the bone substitute stability inside the sinus cavity. Materials and
Methods: Maxillary sinus floor augmentation with lateral approach using sling suture technique
to maintain the collagen membrane against the lateral bone window was performed in 17 patients
(8 women/ 9 men, mean age: 58.2 years). Postoperative cone-beam computed tomography
(CBCT) images up to 6-month follow-up were performed to control the bone graft stability at the
level of the lateral antrostomy. The clinical postoperative pain and swelling were assessed
through a Visual Analogue Scale (VAS) questionnaire from level 1 (low), level 5 (acceptable), to
level 10 (high) at one week postoperative. Results: No bone substitute displacement was
observed for all clinical cases on the CBCT images at 6-month postoperative. The pain and
swelling level observed at one-week post operative were significantly low (respectively
1.6±1.0/2.1± 0.9). Conclusions: Within the limits of this case series, the use of sling suture
technique to maintain the barrier membrane at the level of the lateral bone window in case of
maxillary sinus floor augmentation with lateral approach surgery revealed to be a predictable
protocol to prevent bone substitute displacement outside the sinus cavity.
The International Journal of Oral & Maxillofacial Implants, Pre-Print
DOI: 10.11607/jomi.10723, PubMed-ID: 386073615. Apr. 2024,Seiten: 1-27, Sprache: EnglischGuarnieri, Renzo / Testarelli, Luca / Galindo-Moreno, Pablo / Del Fabbro, Massimo / Testori, TizianoObjectives: The aim of this narrative review is to describe the emerging evidence concerning
etiological factors and pathophysiological mechanisms involved in peri-implant inflammatory
diseases.
Material and Methods: An electronic search for articles published until November 2022 was
conducted in MEDLINE by three independent reviewers to identify manuscripts reporting data on
etiological factors and pathophysiological mechanisms associated with peri-implant diseases.
Results: Current evidence suggests that peri-implant mucositis and peri-implantitis are
inflammatory conditions linked to a microbial challenge. However, in recent years, there has been
increasing evidence indicating that certain peri-implant inflammatory conditions may not be
primarily related to biofilm-mediated infectious processes but rather to other biological
mechanisms, such as a foreign body response.
Conclusion: The current evidence, not only in the dental literature, opens new avenues for a more
complex interpretation of the etiopathogenetic factors involved in peri-implant diseases. A better
understanding of various factors related to the host response, including dysbiosis mechanisms
associated with changes in microbiota composition, is necessary for a more precise physiopathological
characterization of these diseases.
Schlagwörter: Keywords: dental implant; peri-implant diseases; foreign body response; microbial biofilm; periimplant Infection.
International Journal of Periodontics & Restorative Dentistry, Pre-Print
DOI: 10.11607/prd.6778, PubMed-ID: 3819843110. Jan. 2024,Sprache: EnglischPradella, Sandro / Morellini, Chiara / Formentini, Damiano / del Fabbro, MassimoFifty-seven interproximal restorations invading the supracrestal tissue attachment were evaluated over a mean period of 15 years (10-23 years) in terms of crestal bone loss. The distance from the cavity margin to the bone was measured at T0 and controlled using X-rays and a measurable landmark. The mean bone loss in the vertical dimension was 0.46 mm, with a 96.49% survival rate. Smoking habits (p = 0.02) and tooth type (p = 0.03) significantly affected the bone loss. The proposed technique could help the clinician in adopting a minimally invasive approach in the treatment of heavily compromised teeth. Future research with rigorous study designs would be interesting to guide the clinical decision making.
International Journal of Oral Implantology, 2/2024
PubMed-ID: 38801332Seiten: 189-198, Sprache: EnglischTestori, Tiziano / Scaini, Riccardo / Friedland, Bernard / Saibene, Alberto Maria / Felisati, Giovanni / Craig, John R / Deflorian, Matteo / Zuffetti, Francesco / Del Fabbro, Massimo / Wang, Hom-LayMaxillary sinus grafting is a predictable regenerative technique to facilitate maxillary posterior implant placement when there is insufficient vertical bone height inferior to the maxillary sinuses to allow placement of implants of adequate dimensions. It enables an increase in vertical bone height, which makes implant placement easier. Maxillary sinus mucosal membrane perforation is one of the most common intraoperative complications during maxillary sinus grafting and may result in extrusion of graft material into the sinus. When this occurs, the mucociliary function of the maxillary sinus may expel the extruded graft material through its natural ostium, though graft particles may remain in the sinus or possibly occlude the natural ostium. After grafting, transient maxillary sinus mucosal oedema may occur. A postoperative CBCT scan may reveal varying degrees of sinus opacification, namely partial, subtotal or total. Although it is always possible to identify graft material, which may enter the sinus as a result of membrane perforation that might not even be visible to the implantologist during the surgical procedure, it is challenging to assess whether sinus opacification is due to mucosal thickening or mucus accumulation. The aim of the present case series was to offer a pragmatic approach to managing asymptomatic patients whose CBCT scans demonstrated partial, subtotal or total maxillary sinus opacification with bone graft particles that seemed to have been extruded into the sinus.
Schlagwörter: maxillary antrum, maxillary sinus elevation, maxillary sinus grafting, osteomeatal complex, osteomeatal unit, sinus membrane perforation, sinus mucosa, sinus opacification, transient swelling
The authors declare no conflicts of interest relating to this study.
International Journal of Esthetic Dentistry (DE), 2/2024
Clinical ResearchSeiten: 124-136, Sprache: DeutschGalli, Fabio / Deflorian, Matteo / Zucchelli, Giovanni / Del Fabbro, Massimo / Testori, TizianoEine retrospektive Studie mit 5 bis 13 Jahren NachbeobachtungZiel: In der vorliegenden retrospektiven Studie sollten die klinischen Ergebnisse von festsitzendem, auf den Prinzipien der biologisch orientierten Präparationstechnik (BOPT) basierenden Zahnersatz über mittlere bis lange Beobachtungszeiträume ausgewertet werden.
Material und Methoden: Die Behandlungsdokumentation von Patienten, die zwischen Januar 2007 und Dezember 2014 festsitzend rehabilitiert worden waren, wurden retrospektiv ausgewertet. Patienten, deren Akten die Einschlusskriterien erfüllten, wurden außerdem zu einer abschließenden Kontrolluntersuchung einbestellt. Ausgewertet wurden die parodontalen Parameter, das Vorliegen von Gingivarezessionen sowie die aufgetretenen technischen und biologischen Komplikationen.
Ergebnisse: Insgesamt 58 Patienten wurden per Recall eingeladen. Von diesen konnten 52 Patienten mit 220 überkronten Zähnen ausgewertet werden (Ausfallrate: 13,8 %). Die durchschnittliche Beobachtungsdauer waren 9,3 Jahre (Spannweite 5 bis 13 Jahre): 14 Patienten (114 überkronte Zähne) waren 5 bis 8 Jahre, 36 Patienten (106 überkronte Zähne) 9 bis 13 Jahre nachbeobachtet worden. Die prothetische Überlebensrate betrug 99,6 %. An Komplikationen waren eine Wurzelfraktur (0,4 %) und vier Verblendkeramikabplatzungen (1,8 %) dokumentiert. Sechs Zähne (2,7 % der untersuchten Kronen) zeigten eine Gingivarezession von < 1 mm und 13 Zähne (24 Stellen) wiesen eine Sondierungstiefe von 4 mm auf (5,9 % der prothetischen Kronen/1,8 % der sondierten Stellen). Schließlich wurde an 20 Stellen (1,5 %) bzw. 7 Zähnen (3,2 %) Sondierungsbluten beobachtet.
Schlussfolgerungen: Die Präparation nach den BOPT-Regeln (d. h. mit vertikaler, kantenfreier Präparation) führte mittel- bis langfristig zu einem gesunden Parodont und stabiler Gingiva. Das prothetische Behandlungsergebnis blieb dauerhaft erhalten.
Schlagwörter: biologisch orientierte Präparationstechnik, BOPT, parodontale Gesundheit, Gingivarezession, Weichgewebestabilität, retrospektive Studie
International Journal of Esthetic Dentistry (EN), 2/2024
Clinical ResearchPubMed-ID: 38726854Seiten: 112-124, Sprache: EnglischGalli, Fabio / Deflorian, Matteo / Zucchelli, Giovanni / Del Fabbro, Massimo / Testori, TizianoA 5- to 13-year follow-up retrospective studyAim: The present study was a retrospective medium- to long-term follow-up assessment of the clinical outcomes of patients rehabilitated with fixed prostheses according to the biologically oriented preparation technique (BOPT) principles.
Materials and methods: Clinical records of patients rehabilitated between January 2007 and December 2014 were retrospectively assessed. Patients whose records met the inclusion criteria were also recalled for a hygiene visit. Data analyzed included the patients’ periodontal condition, the presence of gingival recessions as well as any technical or biologic prosthetic complication.
Results: Fifty-eight patients were recalled; of these, 52 patients who had received 220 crowns were available for the evaluation (the dropout being 13.8%). The average follow-up was 9.3 years (range 5 to 13 years): 14 patients (114 prosthetic crowns) had a follow-up between 5 and 8 years, and 36 patients (106 prosthetic crowns) between 9 and 13 years. The prosthetic survival rate was 99.6%. One radicular fracture (0.4%) and four chippings of the veneering porcelain (1.8%) were recorded. Six teeth (2.7% of the examined prosthetic crowns) presented gingival recession of < 1 mm, and 13 teeth (24 sites) had a pocket probing depth of 4 mm (5.9% of the prosthetic crowns/1.8% of the sites). Finally, 20 sites (1.5%) in seven teeth (3.2%) showed bleeding on probing.
Conclusions: Tooth preparation according to the BOPT principles (ie, with a vertical finishing line) resulted in medium- to long-term periodontal health and stability of the gingival tissue, and prosthetic success was maintained.
Schlagwörter: BOPT, periodontal health, gingival recession, soft tissue stability, retrospective study
International Journal of Periodontics & Restorative Dentistry, 2/2023
DOI: 10.11607/prd.6463, PubMed-ID: 37232685Seiten: 241-246, Sprache: EnglischOhayon, Laurent / Del Fabbro, MassimoThe aim of this retrospective analysis was to evaluate the clinical and radiographic results of a shortened protocol (using a lateral approach) for early surgical reentry, following a large sinus membrane perforation that occurred during maxillary sinus augmentation (lateral approach), for the rehabilitation of patients with an atrophic posterior maxilla. Between May 2015 and October 2020, seven patients underwent reentry surgery using a lateral approach protocol 1 month after a large sinus membrane perforation during maxillary sinus floor augmentation with lateral approach surgery. All patients presented a residual under-sinus bone height < 3 mm in the posterior maxilla. The sinus membrane was elevated during the reentry surgery, without any difficulty for any patient, using manual blunt elevators or piezoelectric devices, and the sinus floor height was augmented with bone substitute particles. No further perforations were made, and no complications were recorded during the follow-up period from 18 months to 6 years. The 1-month waiting period after the initial sinus surgery allows easy sinus membrane elevation and a lack of complications. This timing could be a feasible option for surgical reentry after a large sinus membrane perforation occurs.
The International Journal of Oral & Maxillofacial Implants, 5/2022
DOI: 10.11607/jomi.9710Seiten: 1003-1025, Sprache: EnglischDel Fabbro, Massimo / Pozzi, Alessandro / Romeo, Davide / de Araújo Nobre, Miguel / Agliardi, EnricoPurpose: To evaluate the performance of fixed complete dental prostheses supported by axial and tilted implants after at least 3 years of follow-up.
Materials and Methods: An electronic search plus a hand search up to April 2021 was undertaken. Clinical studies were selected using specific inclusion criteria, independent of the study design. The main outcomes were cumulative implant survival rate, marginal bone level changes, and complications, after ≥ 3 years of follow-up. The difference in outcomes between axial and tilted implants and between the maxilla and mandible was evaluated using meta-analysis and the Mantel-Cox test.
Results: Out of 824 articles retrieved, 24 were included. In total, 2,637 patients were rehabilitated with 2,735 full prostheses (1,464 maxillary, 1,271 mandibular), supported by 5,594 and 5,611 tilted and axial implants, respectively. In a range between 3 and 18 years of follow-up, 274 implants failed. The cumulative implant survival rate was 93.91% and 99.31% for implants and prostheses, respectively. The mean marginal bone level change was moderate, exceeding 2 mm in only two studies. Marginal bone loss was significantly lower around axial compared with tilted implants (P < .0001), whereas it was not affected by arch (maxilla vs mandible; P = .17).
Conclusion: Fixed complete dental prostheses supported by tilted and axially placed implants represent a predictable option for the rehabilitation of edentulous arches. Further randomized trials are needed to determine the efficacy of this surgical approach and the remodeling pattern of marginal bone in the long term.
Schlagwörter: axial implants, immediate loading, mandible, marginal bone loss, maxilla, tilted implants
International Journal of Periodontics & Restorative Dentistry, 4/2022
DOI: 10.11607/prd.5833Seiten: 471-477, Sprache: EnglischTestori, Tiziano / Deflorian, Matteo / Scaini, Riccardo / Wang, I-Ching / Zucchelli, Giovanni / Steigmann, Marius / Del Fabbro, Massimo / Wang, Hom-Lay / Francetti, LucaCommon challenges encountered for atrophic maxilla rehabilitation are the inadequate width and height of attached keratinized mucosa (AKM) and shallow vestibular depth. This study presents a buccally displaced palatal (BDP) flap technique to increase the tissue thickness and AKM width at the second-stage surgery and reestablish the correct fornix depth. The peri-implant pocket depths, modified Plaque Index score, modified sulcus Bleeding Index score, and soft tissue recession were evaluated 6 and 12 months after prostheses loading. A total of 52 implants were placed and analyzed, and no implant failures were found. No significant changes in peri-implant parameters were observed between 6 and 12 months, and mean recession was less than 0.2 mm after 12 months. Though this change was statistically significant, it was clinically irrelevant. The results demonstrate that adequately healthy peri-implant soft tissues and substantial dimensional stability of vestibular soft tissues at the 1-year follow-up were achieved with the BDP flap technique. The BDP flap could represent a viable option for increasing the width and the height of AKM and establishing the correct maxillary fornix depth.
International Journal of Periodontics & Restorative Dentistry, 3/2022
DOI: 10.11607/prd.5571Seiten: 311-318, Sprache: EnglischTestori, Tiziano / Yu, Shan-Huey / Scaini, Riccardo / Rosano, Gabriele / Tavelli, Lorenzo / Del Fabbro, Massimo / Francetti, Luca / Wang, Hom-LayMaxillary sinus wall fenestration at the lateral wall or floor of the sinus can result from many potential factors, such as the repair of oro-antral communication, Caldwell-Luc antrostomy, tooth extraction after an endodontic or periodontal infection that eroded the sinus wall, and the combination of sinus pneumatization and alveolar ridge resorption after teeth removal. When sinus wall fenestration is observed on radiographs, it usually indicates adhesion between the sinus membrane and buccal flap, which makes the reentry surgery for subsequent sinus augmentation challenging. To minimize surgical complications in these challenging scenarios, this paper presents a split-flap surgical technique for the management of soft tissue adhesion between the sinus membrane and alveolar mucosa when attempting a lateral window sinus augmentation.