Purpose: The aim of this study was to compare the core survival rates (CSRs) of cast metal versus resin core restorations luted with adhesive resin cement, as well as to determine the risk factors for core failure. Materials and Methods: Nine hundred ninety-one patients (2,124 cores) who received either cast metal or resin cores luted with adhesive resin cement at the Fixed Prosthodontic Clinic of Okayama University Dental Hospital between April 1988 and December 1991 and whose structured clinical core record was filled appropriately comprised the study subjects. The clinical core record included information regarding patient age, sex, core restoration type, tooth location, tooth type, remaining coronal dentin, and root canal form. CSRs, as well as causes for failure, were analyzed 15 years postinsertion. Since 381 patients lacked data regarding predictors for core failure, a subsample of 610 patients (1,053 cores) was used for the subsequent risk factor analysis. Results: The cumulative CSR of resin cores (78.7%) was significantly higher than that of cast metal cores (55.4%; log-rank test, P .0001). The Cox proportional hazards test revealed that sex (male, P .0001), absence of remaining coronal dentin (P = .0057), core restoration type (cast metal, P = .0186), and higher age at core insertion (P = .0380) were significant predictors for core failure. The incidence of complications, such as core loosening (P = .0016) and tooth extraction (P .0001), was significantly higher in cast metal cores. Conclusions: Cast metal cores were associated with a significantly lower CSR than resin cores, and significant risk factors for core failure were sex (male), absence of remaining coronal dentin, core restoration type (cast metal), and higher age at core insertion.