This study investigated the compressive strength of all-ceramic crowns manufactured using two recently introduced systems. The mean forces of fracture were 964 N for In-Ceram crowns, 814 N for paint-on IPS Empress crowns, and 750 N for layered IPS Empress crowns, compared with 1,494 N for metal ceramic crowns veneered on a nickel-chromium coping. The results indicate that clinical testing of these all-ceramic crowns is reasonable. Controlled, clinical, long-term evaluation is necessary to assess the safe application of these new crown systems.