Inflammation

The fifth edition of this popular textbook includes a new clinical section and additional illustrations. The authors create a refreshing self-study approach using direct langua and helpful metaphors. Self tests are strategically placed f the board examinations, or as a refresher for busy practitioners who want to stay abreast of this rapidly advancing field. Clearly written, with numerous illustration and tables.

Contents
Part I: Acute Inflammatory Process

• Preface
• Introduction
• Abbreviations
• Vascular Response to Injury
• Quick Review
• The vascular events
• Exudation, transudation, and edema
• The lymphatic system
• Postscript

Chemical Mediators of the Vascular Response

• Histamine
• Serotonin
• Plasma proteases
• The kinin system
• The fibrinolytic system
• Advice from some old friends
• The complement system
• Eicosanoids
• Platelet activating factor
• Nitric oxide
• Neuropeptides
• Other mediators
• Pain associated with acute inflammation

The Blood Leukocytes

• The cells involved
• The individual leukocytes
• The mononuclear-phagocytic system

Systemic Manifestations of Inflammation

Part II: Immunity
The Immune System

• The opponents
• The defenders
• Antigen-presenting cells
• The system
• Immunoglobulins
• General battle plan
• Duration of antibody response

Hypersensitivity Reactions

• Type I - immediate-type hypersensitivity
• Type II - Immune cytotoxic reactions
• Type III - Immune complex hypersensitivity
• Type IV - Delayed-type hypersensitivity
• Immunologic tolerance
• Immunodeficiency

Chronic Inflammatory Processes

• General considerations
• Causes of chronic inflammation
• Factors contributing to chronicity
• Maintenance of chronicity
• Other cells involved
• Tissue damage
• Chemical mediators
• Essential elements
• Granulomatous inflammation
• Control of inflammation

Part III: Repair of Host Tissues
Healing

• Resolution vs repair
• Regeneration
• Fibrous repair
• Cell-matrix interaction
• Cell-cell interaction
• The role cells play in wound healing
• What is organization?
• Epithelialization
• Strength of healing wounds
• Remodelling of wounds
• Local and systematic factors influencing healing

Part IV: Application of Basic Principles
Clinical Connections

• Inflammation of the tooth pulp (pulpitis)
• Inflammatory lesions of the periapical tissues
• Acute pyogenic osteomyelitis of the jaws
• Chronic osteomyelitis of the jaws
• Cellulitis
• Periodontal disease
• Acquired immunodeficiency syndrome
• Answers to Self-Test and Charts

Index