Purpose: The purpose of this study was to evaluate clinical treatment outcome of fixed prostheses in different sizes and with combinations of different numbers of teeth and implants as abutments. Materials and Methods: A total of 115 implants were placed in 36 patients, 75 (65%) in the maxilla and 40 (35%) in the mandible. The implants were connected to 85 abutment teeth, 50 in the maxilla and 35 in the mandible. Of the prosthetic restorations, 19 were gold ceramic, 17 were gold acrylic, three were titanium acrylic, one was titanium ceramic, and one was titanium composite. The observation period ranged from 14 months to 8.9 years. The treatments comprised both fixed partial dentures supported by one tooth and one implant as well as complete-arch fixed prostheses supported by a number of teeth and implants. Results: A total of nine implants were lost, three during healing and six after loading. The postloading cumulative implant survival rate was 89.8% after 5 years. Five abutment teeth were lost, and of the 41 prostheses included in the study, only two (5%) were lost during the observation period. Marginal bone loss was registered around 46 implants at the 1-year follow-up examination. During the following observation period, only slight changes in the marginal bone level adjacent to the implants and teeth were registered. The magnitude of technical complications was low. Conclusion: This investigation confirms the findings in similar studies that treatments with periodontally healthy teeth and implants splinted together in rigid one-piece superstructures show excellent long-term follow-up results.