Long-term denture wearers undergo facial changes as a result of occlusal wear of the dentures and residual ridge resorption. This study examined 12 such patients, presenting with a clinical appearance of Angle's Class III occlusal relationships, to evaluate a clinical method of determining the correct mandibular position. Complete dentures were fabricated for each patient using standard clinical procedures, but acrylic resin blocks were left on the mandibular posterior bases instead of denture teeth. Ensuing changes in maxillomandibular relationships were recorded. After the stabilization of the mandibular relationship, the dentures were completed using mandibular posterior teeth. Patients were evaluated using cephalometric analysis before and after treatment. Results show that a careful procedure of denture fabrication allows the determination of the correct mandibular relationship, even in patients who have experienced extreme facial collapse.