Adhesively luted all-ceramic inlay-retained fixed partial dentures can be a clinical alternative for the replacement of missing posterior teeth in certain situations. This type of restoration allows satisfactory esthetics and reduced tooth preparation compared to a conventional metal-ceramic fixed restoration. This case report describes the use of an inlay-retained fixed partial denture as a conservative alternative for the replacement of missing posterior teeth. Keywords: missing posterior teeth, all-ceramic, inlay fixed partial denture