Introduction: Oral potentially malignant disorders (OPMDs) are a group of conditions that have the potential to transform into cancer if left untreated. Approximately 16–62% of OPMDs undergo a malignant transformation and eventually develop into oral squamous cell carcinoma (OSCC). The five-year survival rates of OSCC patients decrease from 80 to 40% if diagnosed at an advanced stage. Early detection of OPMD allows for prompt intervention and treatment. Although biopsy is the gold standard, patients still prefer a non-invasive approach for diagnosing his/her disease.
Aim: This poster aims to present a review on the current advances in non-invasive tools for early diagnosis of oral potentially malignant disorders.
Method: A comprehensive search of online databases including Pubmed, Medline and Scopus were conducted to identify studies from (January 2010 to Dec 2022) using search keywords ‘Oral screening devices’, ‘autofluorescence’, ‘chemiluminescence’, ‘oral malignant lesions’, ‘imaging techniques’, ‘non-invasive tools’, ‘oral dysplasia’, etc. A total of 24 studies were reviewed and evaluated based on their sensitivity and specificity.
Result: Results of the studies were tabulated and representation of their sensitivity and specificity was done to evaluate the diagnostic accuracy.
Conclusion: None of the analysed techniques based on assessing oral images can replace biopsy. Further studies are needed to explore the role of these emerging techniques to identify an early non-invasive screening method for early detection of OPMDs.
Keywords: autofluorescence, chemiluminescence, imaging techniques, non-invasive tools, oral dysplasia, oral malignant lesions, oral screening devices, oral potentially malignant disorders
